Beonchip – Be-Gradient (box of 10 chips)
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Flow Gradient is Beonchip’s device designed for the application of electrochemical gradients to 3D cell cultures.
Be-Gradient is compatible with any type of optical microscopy (inverted phase contrast, confocal, fluorescence). Be-Gradient consists of a cell culture chamber and two channels in direct contact with it. Changing the concentration of one element between the channels on both sides of the central chamber results in the creation of a chemical gradient. For barrier and vasculature models, the lateral channels are meant to simulate blood vessels, where endothelial cells can be cultured.
Pack of 10 items.
Benefits:
- Easy to use: Be-Gradient is compatible with any type of optical microscopy (confocal, fluorescence…) and its slide format has been chosen for easy handling under a microscope.
- Easy to implement: Be-Gradient chambers are positioned in standard positions of a 96 well plate for its use in automated microscopes.
- Easy to connect: Be-Gradient is compatible with all microfluidic flow control systems (syringe, peristaltic pumps, pressure control systems, rocker systems…).
- No unspecific absorption: Unlike in other PDMS devices, Be-Gradientis made of lipophobic thermoplastic materials and does not present unspecific drug absorption issues. Therefore, it allows immunohistochemistry with fluorescent detection.
- Cell recovery option: The cell cultures used in the Be–Gradient can be easily recovered for further experimentation
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